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2015 News


December 2015

Calyxt and PBL Announce Research Collaboration and Licensing Agreement for Trait Development in Wheat, Rice and Corn

December 16, 2015 — New Brighton, Minn. — Calyxt, Inc., a Minnesota-based company focused on developing healthier food products to benefit both consumers and farmers, today announced that it has signed a research collaboration and option to exclusive licenses with Plant Bioscience Limited (PBL) for certain new crop plants developed using gene editing by the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences in Beijing. Plants with new traits in wheat, rice and corn are currently at various stages of development using gene-editing technology and include quality improvement and yield increase traits.

Please click here to read the article in full.

For more information, please contact Dr Jan Chojecki.

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December 2015

PBL Signs License Agreement for Baulcombe & Hamilton RNAi patent

Norwich, UK 1 December 2015-- Plant Bioscience Limited (PBL), a technology development and intellectual property (IP) management company, announced today that it has entered into a licensing agreement that grants Thermo Fisher Scientific a world-wide, non-exclusive license to the Baulcombe patents (U.S. Patent Nos. 6,753,139, 7,704,688, 8,097,710, 8,258,285, 8,263,569, 8,299,235, 8,349,607, 8,759,102 and 8,779,236) for use in the field of research reagents and kits.  Financial terms were not disclosed.

Please click here for the full press release or here for a link to the Short RNA section on our website.

For licensing enquiries, please contact Dr Lars von Borcke (lars@pbltechnology.com).  All other enquiries to info@pbltechnology.com.

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October 2015

GW7: yield and grain quality

Inventors of the GW7 technology (Tech ID 14.587) have published their most recent work in Nature Genetics.  The article is entitled The OsSPL16-GW7 regulatory module determines grain shape and simultaneously improves rice yield and grain quality.

For more information or for commercial opportunities, please contact Dr Jan Chojecki.

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October 2015

SOD7/NGAL3 technology for increased seed size, plant growth and grain yield

Inventors of the SOD7/NGAL3 technology (Tech ID 14.586) have published their most recent work in Plant Cell.  The article is entitled Transcription Factors SOD7/NGAL2 and DPA4/NGAL3 Act Redundantly to Regulate Seed Size by Directly Repressing KLU Expression in Arabidopsis thaliana.

For more information or for commercial opportunities, please contact Dr Jan Chojecki.

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October 2015

Beneforté Broccoli features on BBC Countryfile (25 October)

The Beneforté broccoli story was featured on BBC TV’s Countryfile programme on 25 October,  and can be watched on the BBC iPlayer.   Beneforté broccoli is now being grown commercially in the UK and elsewhere around the world and is available in a number of leading supermarkets in the UK including Marks & Spencer and Asda.

Beneforté broccoli was bred, using conventional techniques, by Professor Richard Mithen at the John Innes Centre, and Professor Mithen is continuing his work on broccoli by studying potential health benefits of the broccoli, and glucoraphanin, at the Institute of Food Research.

Research from human trials with 130 volunteers, and published earlier this year, showed that including this broccoli in the diet for 12 weeks reduced the levels of LDL-cholesterol by an average of about 6%. Further human nutrition trials are ongoing.

For more information about the science behind broccoli, glucoraphanin, and the development of Beneforté visit: http://www.superbroccoli.info/.



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September 2015

Photosynthesis Gene Can Help Crops Grow in Adverse Conditions

Paul Jarvis and colleagues have published their most recent work on SP1 technology (PBL Tech ID 13.568).  The paper which is published in Current Biology is entitled “Regulation of Chloroplast Protein Import by the Ubiquitin E3 Ligase SP1 Is Important for Stress Tolerance in Plants”.  PBL is managing the commercial development of this important innovation.

Please click here for the Oxford University press release.

For more information please go the 13.568 SP1 page, or for commercial opportunities, please contact Dr Jan Chojecki.
 

 

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July 2015

PBL partners with Calyxt to develop disease resistant wheat

Calyxt, Inc., a Minnesota-based company focusing on developing healthier food products, today announced that it has signed an exclusive license agreement with Plant Bioscience Limited (PBL) for a bread wheat trait generated using gene editing. The trait provides endogenous resistance to powdery mildew of wheat, a fungus widely distributed throughout the world, responsible for major grain and yield losses.

Please click here to read the article in full.

For more information, please contact Dr Jan Chojecki.

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April 2015

High glucoraphanin broccoli reduces cholesterol: new research studies published on Beneforté broccoli

Two independent studies have now shown that including Beneforté broccoli in the diet reduces blood LDL-cholesterol levels by around 6%, according to the results of human trials led by the Institute of Food Research.

Reference: “A diet rich in high glucoraphanin broccoli reduces plasma LDL cholesterol: evidence from randomised controlled trials”, Armah, C.N. Molecular Nutrition and Food Research. DOI 10.1002/mnfr.201400863.

Please click here to read the article in full.

For more information, please contact Dr Jan Chojecki.

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March 2015

PBL’s patent on glucoraphanin-rich broccoli : Valid

European Patent Office Decision confirms societal value and validity of patents for innovative plant breeding

The decision of the European Patent Office Enlarged Board of Appeal, 25th March 2015 on Case Number G 2/13, is welcome news as it provides much needed clarity on the scope of patent protection in the European Union for plants and plant products.  Certain of the claims in PBL’s European patent  on high-glucoraphanin broccoli (Application Number 99915886.8 / Patent Number EP1069819), produced during the 1990’s by Prof Richard Mithen while at the John Innes Centre, have been questioned as to whether they should be excluded from patentability under Article 53(b) of the European Patent Convention.  The EBA has now interpreted the scope of the exclusion from patentability under Article 53(b) EPC such that all PBL’s patent claims should be allowable.  The “broccoli patent” has been seen as something of a test case and this decision represents an important step towards encouraging much needed innovation in agriculture and horticulture in the European Union.

Please click here to read the article in full.

Professor Mithen has continued his research into the nutritional impact of consuming glucoraphanin-rich broccoli. The broccoli is marketed under the name Beneforté Broccoli and more information is available on the Glucoraphanin Enriched Broccoli page of our website and at www.superbroccoli.info.

Please click here for JIC's statement on the EBA ruling.

For more information, please contact Dr Jan Chojecki.

The inventors named on the patent on glucoraphanin-enriched broccoli are Richard Mithen and Kathy Faulkner.

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February 2015

PBL's partner Medicago announces new contract to explore production of Ebola antibodies

Medicago, PBL’s licensee of the Hyper Trans technology, announced today that it has received a task order from the Biomedical Advanced Research and Development Authority (BARDA) at the US Department of Health and Human Services (HHS) for three anti-Ebola virus monoclonal antibodies (mAbs) with expected performance comparable to that of ZMapp™, from Mapp Biopharmaceutical.

Please click here to read article in full, and here for a link to the CPMV-HT section on our website.


Previous Medicago news items:

Jul 2013 Medicago announces agreement to be acquired by Mitsubishi Tanabe Pharma in a transaction valued at $357M
Mar 2012 CONGRATULATIONS to Prof George Lomonossoff
Jan 2011 Medicago selected to collaborate with IDRI on a multimillion dollar grant awarded to IDRI from the US Department of Defense
Aug 2009 PBL / John Innes Centre technology instrumental in Medicago’s flu vaccine production
May 2009 Medicago Receives 2009 Genesis Innovation Award
Aug 2006 Medicago and PBL sign license agreements for PBL’s bipartite expression and related technologies

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