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07.434 - Clostridium Difficile Endolysin

Patent Reference:
International Patent Publication Nos. WO2009/068858 and WO2010/136754.

Prof Mike Gasson
Institute of Food Research (Norfolk, UK)

A lead biologic for the treatment of 
Clostridium difficile associated disease (CDAD). 

Highly species-specific endolysin targets all major pathogenic strains of C. difficile. 


Melinda J Mayer, Arjan Narbad, and Michael J Gasson (2008). Molecular Characterization of a Clostridium difficile Bacteriophage and Its Cloned Biologically Active Endolysin. Journal of Bacteriology; Vol 190, No 20: 6734-6740. 

Contact: Dr Martin Stocks

Download non-confidential summary (PDF): Click here

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