Orientin Production

Tech ID: 23.702

Key Features

• Genes and production system for efficient orientin and isoorientin flavonoid production in duckweed
• Overexpression of LtP1-L to increase orientin and isorientin production

Description

Dr Shengjun Li and researchers at Qingdao Institute of Bioenergy and Bioprocess Technology, China have identified novel P1-L genes from the duckweed stains Lemna turionifera and Landoltia punctata and created transgenic Lemna turionifera duckweed stains that through over expression of LtP1-L and/or LeP1-1 produce high levels of orientin and isoorientin flavonoids, released in aqueous solution. LtP1L is key in accumulating CFGs, opens up the potential for further metabolic engineering approaches in duckweed for high flavone accumulation.

For further detailed information please download the non-confidential summary pdf.

Patents

Published: WO2024/110539 A1

References

Wang S, He G, Liu Y, Wang Y, Ma Y, Fu C, Xu H, Hu R, Li S (2024). A P1-like MYB transcription factor boosts biosynthesis and transport of C-glycosylated flavones in duckweed. International Journal of Biological Macromolecules; 277(2): 134138. https://doi.org/10.1016/j.ijbiomac.2024.134138