UPL2/LARGE2 - Increased Seed Number in grain crops

Tech ID: 20.672

Key Features

• Increasing yield components by mutations or edits to reduce UPL2 function.
• Practical demonstration in wheat, millet and oil-seed rape.

Description

Dr Yunhai Li and his team at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, have discovered that LARGE2 encodes a HECT-domain E3 ubiquitin ligase UPL2.

For further detailed information please download the non-confidential summary pdf.

Patents

Published: WO/2022/136658; CN 116709908A

References

Luojiang Huang et al (2021). The LARGE2-APO1/APO2 regulatory module controls panicle size and grain number in rice. The Plant Cell; 33(4): 1212-1228. https://doi.org/10.1093/plcell/koab041